Molecular docking analysis of curcumin analogues against kinase domain of ALK5
نویسندگان
چکیده
منابع مشابه
Molecular docking analysis of curcumin analogues with COX-2
Curcumin analogues were evaluated for COX-2 inhibitory as anti-inflammatory activities. The designed analogues significantly enhance COX-2 selectivity. The three compounds could dock into the active site of COX-2 successfully. The binding energies of -8.2, - 7.6 and -7.5 kcal/mol were obtained for three analogues of curcumin respectively. Molecular docking study revealed the binding orientation...
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An efficient synthesis of polyhydroquinoline derivatives is achieved via Hantzsch condensation reaction between aldehydes, dimedone, ethyl acetoacetate and ammonium acetate in the presence of catalytic amount of SFHS in ethanol. This method gives remarkable advantages such as shorter reaction time, simple workup procedure and good to excellent yields. Furthermore the catalyst can be recovered c...
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An efficient synthesis of polyhydroquinoline derivatives is achieved via Hantzsch condensation reaction between aldehydes, dimedone, ethyl acetoacetate and ammonium acetate in the presence of catalytic amount of SFHS in ethanol. This method gives remarkable advantages such as shorter reaction time, simple workup procedure and good to excellent yields. Furthermore the catalyst can be recovered c...
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ژورنال
عنوان ژورنال: In Silico Pharmacology
سال: 2017
ISSN: 2193-9616
DOI: 10.1007/s40203-017-0034-0